A Biostatistical Evaluation of Recent Smoked Tobacco Usage on Serum Triglyceride Levels and Cardiovascular Risk Indicators in Adults and Adolescents.
DOI:
https://doi.org/10.58445/rars.3962Keywords:
NHANES, smoked-tobacco use, serum triglycerides, cardiovascular risk, nicotine exposureAbstract
Using data from NHANES, this study analyses the relationship between recent smoked-tobacco use and serum triglyceride levels in adults and adolescents. The independent variable was recent smoked-tobacco use, and this data is collected from a CDC questionnaire. The dependent variable of this data is the triglyceride levels in the participants. Every participant had a sequence number (SEQN) and using that number, the questionnaire dataset and the participant triglyceride level dataset was merged using Jamovi software. The final sample contained 3,055 participants, with 420 recent smoked-tobacco users and 2,635 participants who did not report smoked-tobacco use within the past five days. The study resulted in smoked-tobacco users had a higher average triglyceride level than non-users, with recent smoked-tobacco users having a triglyceride level of 138 mg/dL compared to non-users having a triglyceride level of 113 mg/dL. The statistical significance of this analyses was proven using a Welch's t-test and it resulted in a p-value of less than 0.001. The results of this study included that on average, recent smoked-tobacco users have higher triglyceride levels.
References
American Heart Association. (2026). HDL (good), LDL (bad) cholesterol and triglycerides. https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides
Andersson, K., & Arner, P. (2001). Systemic nicotine stimulates human adipose tissue lipolysis through local cholinergic and catecholaminergic receptors. The Journal of Clinical Endocrinology & Metabolism, 86(3), 1221–1226. https://pubmed.ncbi.nlm.nih.gov/11477508/
Benowitz, N. L. (2016). Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends in Cardiovascular Medicine, 26(6), 515–523. https://doi.org/10.1016/j.tcm.2016.03.001
Centers for Disease Control and Prevention. (n.d.). About the National Health and Nutrition Examination Survey. National Center for Health Statistics. https://www.cdc.gov/nchs/nhanes/about/index.html
Centers for Disease Control and Prevention. (2024a). National Health and Nutrition Examination Survey: August 2021–August 2023 smoking—recent tobacco use questionnaire (SMQRTU_L). U.S. Department of Health and Human Services, National Center for Health Statistics. https://wwwn.cdc.gov/Nchs/Data/Nhanes/Public/2021/DataFiles/SMQRTU_L.htm
Centers for Disease Control and Prevention. (2024b). Tobacco product use among middle and high school students—United States, 2024. Morbidity and Mortality Weekly Report, 73(41), 913–919. https://www.cdc.gov/mmwr/volumes/73/wr/mm7341a2.htm
Centers for Disease Control and Prevention. (2024c). National Health and Nutrition Examination Survey: August 2021–August 2023 data documentation, codebook, and frequencies: Cholesterol—LDL & triglycerides (TRIGLY_L). U.S. Department of Health and Human Services, National Center for Health Statistics. https://wwwn.cdc.gov/Nchs/Data/Nhanes/Public/2021/DataFiles/TRIGLY_L.htm
Lau, E. (2020). E-cigarette use negatively affects lipid levels and myocardial blood flow. Massachusetts General Hospital: Advances in Motion. https://advances.massgeneral.org/cardiovascular/article-external.aspx?id=1084
Nordestgaard, B. G., Benn, M., Schnohr, P., & Tybjærg-Hansen, A. (2007). Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA, 298(3), 299–308. https://pubmed.ncbi.nlm.nih.gov/17635890/
Zeller, M., Chague, F., Maza, M., Bichat, F., Cottin, Y., & Farnier, M. (2024). Characteristics and prognosis of patients with elevated triglycerides in acute myocardial infarction: Observational data from a large database over a 17-year period. Journal of Clinical Lipidology, 18(1), e38–e43. https://doi.org/10.1016/j.jacl.2023.11.004
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