Preprint / Version 1

Physical Exercise Can Fight Alzheimer’s Disease

##article.authors##

  • Rahini Chanda Dougherty Valley High School

DOI:

https://doi.org/10.58445/rars.4026

Keywords:

Alzheimer's Disease, Exercise, Cognitive Decline, Prevention, Healthcare

Abstract

Alzheimer’s disease (AD) is a very common and prevalent type of dementia, affecting millions of people in the world, and there is no current cure. However, current research and several studies have shown that healthy lifestyle habits, especially physical exercise, can help with the prevention of AD. The purpose of this literature review is to analyze existing research on how physical exercise affects the risk of AD and its progression. This review will discuss how brain blood flow, healthy lifestyle changes, and exercise hormones affect AD. The studies discussed in this review have found that physical exercise consistently improves general brain health and reduces the progression of AD, which can be a temporary solution to helping AD patients until a real treatment is found. While there are some limitations of the studies, such as few of them involving lab animals rather than actual human subjects, the results are promising and suggest that physical exercise can reduce the risks of AD and related issues overall.

References

Alzheimer's Association. (2026). What is Alzheimer's Disease? Alzheimer's Association. Retrieved July 29, 2026, from https://www.alz.org/alzheimers-dementia/what-is-alzheimers

Mayo Clinic Staff. (2026, March 3). Alzheimer's disease. Mayo Clinic. Retrieved July 29, 2026, from https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/symptoms-causes/syc-20350447

Harrington Discovery Institute. (2022, November 16). Can Individualized Exercise Slow Alzheimer's Disease? Harrington Discovery Institute. Retrieved July 29, 2026, from https://www.harringtondiscovery.org/blog/2022/11/16/can-individualized-exercise-slow-alzheimers-disease

Alzheimer's Association. (n.d.). Get Moving. Alzheimer's Association. Retrieved July 29, 2026, from https://www.alz.org/help-support/brain_health/get-moving

Islam, M. R., Valaris, S., Young, M. F., Haley, E. B., Luo, R., Bond, S. F., Mazuera, S., Kitchen, R. R., Caldarone, B. J., Bettio, L. E. B., Christie, B. R., Schmider, A. B., Soberman, R. J., Besnard, A., Jedrychowski, M. P., Kim, H., Tu, H., Kim, E., Choi, S. H., . . . Wrann, C. D. (2021). Exercise hormone irisin is a critical regulator of cognitive function. Nature Metabolism, 3(8), 1058-1070. https://doi.org/10.1038/s42255-021-00438-z

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Posted

2026-08-09